Gain-of-function variants in KCNT1 have also been found in patients with other epileptic syndromes, including autosomal dominant nocturnal frontal lobe epilepsy, Ohtahara syndrome, and Lennox-Gastaut syndrome (3, 5, 7, 8, 20, 21). This evidence concerns the gene KCNT1 and autosomal dominant nocturnal frontal lobe epilepsy.