Furthermore, there was higher risk of CAD in patients with LDLR rs749038326 (OR, 2.14; 95% CI, 1.31–3.50, p = 0.002), and an approximately 4-fold increased risk of AMI in individuals with the LDLR rs730882109 polymorphism (OR, 3.79; 95% CI, 2.26–6.35, p < 0.0001), compared with the non-FH controls. This evidence concerns the gene LDLR and coronary artery disorder.