Furthermore, there are data about the association between depression and specific variants of genes involved in serotonin synthesis and signaling, including TPH2 (Zill et al., 2004), serotonin receptors (Lemonde et al., 2003), and serotonin transporter (SERT) (Hoefgen et al., 2005; Avshalom et al., 2010). The gene discussed is SLC6A4; the disease is depressive disorder.