Findings from our longitudinal study are consistent with published data on the humoral immune response in the milk of women with COVID-19 (6–8) and show: (1) that the milk of most women with COVID-19 have anti-RBD IgA and IgG; (2) that RBD-specific antibodies are present in the milk of most women for at least four-months after a COVID-19 positive test; and (3) the presence of a robust RBD-specific IgA response in milk but a lack thereof in circulation. This evidence concerns the gene CD79A and COVID-19.