We noticed that ST3GAL5 upregulation (p < 0.001) and ST3GAL6 downregulation (p < 0.001) were confirmed in ccRCC tissues (n = 530), comparing with their paired normal kidney tissues (n = 72), from TCGA-KIRC dataset (Figure 1E). Here, ST3GAL6 is linked to nonpapillary renal cell carcinoma.