STING1 and neurodegenerative disease: While the association of STING with neurodegenerative diseases has been poorly investigated in previous studies, the activation of the immune system is a prominent feature of several neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), frontotemporal dementia (FTD), multiple sclerosis (MS), and ALS.