STING1 and infection: found that host infection with HSV results in the formation of nitro fatty acids in vivo and that endogenous nitro fatty acids (NO2-Fas) can covalently modify STING by Michael addition reaction to adjacent cysteines at positions 88 and 91 (Cys88/91) or N-terminal histidine (His16), thereby inhibiting the palmitoylation of STING and subsequent production of IFNs in host cells (Figure 17) (179).