RUNX2 and neoplasm: They were as follows (1): myeloid cells highly expressing CD74, CD14, and lysozyme (2); TILs, including T and NK cells, specifically expressing CD3D, CD3E, and NKG7 (3); osteoclast-like giant cells with high expression of ACP5, CTSK, and MMP9 (4); tumor cells highly expressing BGLAP, RUNX2, RANKL, and IBSP (5); fibroblasts specifically expressing FN1, LUM, and DCN (6); endotheliocytes specifically expressing VWF, RAMP2, and CDH5; and (7) pericytes highly expressing RGS5, ACTA2, and MCAM (Figure 1C;Supplementary Figure S1A).