Other upregulated miRs included amongst others miR-1303, which regulates ADAM33 (59), miR-204, which regulates bronchial smooth muscle cell proliferation (105), miR-299, which is down-regulated in asthma (49), IL-13-induced miR-379 (106) and miR-485 up-regulated in asthma (102). This evidence concerns the gene ADAM33 and asthma.