PRTN3 and rheumatoid arthritis: A study including over 500 patients from two established cohorts who fulfilled the 1987 criteria at 1 year but not at inclusion found that when applying the 2010 criteria 57% and 75% of these patients, respectively, would have been identified as RA already at inclusion.18 Among the ACPA-positive patients, the early detection based on 2010 criteria was approx. 92%.