Moreover, tan I, CPT, and tan IIA share common targets, including miR-137 and let-7a-5p, which function in inhibiting the proliferation of NSCLC by regulating the expression of ULK2/IBTK and AURKA, respectively; these common targets may be a result of highly similar chemical structures (Zhang et al., 2016; Liu et al., 2020a). The gene discussed is AURKA; the disease is non-small cell lung carcinoma.