Tan IIA suppresses the proliferation of AML cells (HL-60 and THP-1), glioma cells, esophageal cancer cells (EC109), breast cancer cells, and NSCLC cells through targeting miR-497-5p/Akt3, miR-122/PKM2, miR-16-5p/TLN1, miR-125b/STAR13, and let-7a-5p/aurora kinase A (AURKA), respectively (Zhang et al., 2016; Liu et al., 2020a; Liu et al., 2020; Nie et al., 2020; You et al., 2020; Li et al., 2022). This evidence concerns the gene AURKA and esophageal cancer.