MYD88 and non-small cell lung carcinoma: Furthermore, UA downregulates miR-499a-5/secreted frizzled related protein 4 (sFRP4) and miR-149-5p/myeloid differentiation primary response 88 (MyD88), thereby inhibiting the proliferation of NSCLC cells (Chen et al., 2020; Mandal et al., 2021).