In non-APL AML patients of TCGA-LAML datasets, a total of 249 survival correlated genes (according to the criteria ∣log2FC∣ > 1 and adjusted p < 0.05) performed 6-fold cross-validation and 9 genes in addition to ECHDC3 were finally found with regression coefficients, namely, RPS6KL1, RELL2, FAM64A, SPATS2L, MEIS3P1, CDCP1, CD276, IL1R2, and OLFML2A (Figures S2A–C). Here, ECHDC3 is linked to acute promyelocytic leukemia.