In non-APL AML patients of TCGA-LAML datasets, a total of 249 survival correlated genes (according to the criteria ∣log2FC∣ > 1 and adjusted p < 0.05) performed 6-fold cross-validation and 9 genes in addition to ECHDC3 were finally found with regression coefficients, namely, RPS6KL1, RELL2, FAM64A, SPATS2L, MEIS3P1, CDCP1, CD276, IL1R2, and OLFML2A (Figures S2A–C). The gene discussed is PIMREG; the disease is acute promyelocytic leukemia.