Some cell clusters are described in detail below: Tyrosine hydroxylase (TH) and Chromogranin A (CgA or CHGA) positive pheochromocytoma tumor cells (Figures 1B, C), Protein Tyrosine Phosphatase Receptor Type C (PTPRC) positive immune cells (Figure 1D), Von Willebrand factor (VWF), Platelet and Endothelial Cell Adhesion Molecule 1 (PECAM1) and Plasmalemma Vesicle Associated Protein (PLVAP) positive endothelium Cells (Figures 1E–G), Actin Alpha 2 (ACTA2 or α-SMA) and Platelet derived growth factor receptor B (PDGFRB) positive fibroblasts (Figures 1H, I). The gene discussed is ACTA1; the disease is hereditary pheochromocytoma-paraganglioma.