ADAM members (9, 10, 12, 17, 23, 28), ADAMTS (a disintegrin and metalloprotease with thrombospondin motifs) members (6, 7, 8, 9, 10, 12, 13, 15, 20), ADAMTSL1 (ADAMTS-like protein 1), and ADAMDEC1 were increased in GBM, while ADAM members (11, 15, 20, 32, 33) and ADAMTS members (1, 18) were decreased in GBM (Figure 1A). Here, ADAMDEC1 is linked to glioblastoma.