In addition, ChIP analysis demonstrated that CDX2 binds to the regulatory region of hST8GalNAc I gene in Caco-2 cells and human intestinal metaplasia and luciferase reporter assay showed that CDX2 transactivates the regulatory region of hST8GalNAc I gene in human gastric carcinoma cell lines AGS and MKN45 (Pinto et al., 2015). Here, CDX2 is linked to gastric carcinoma.