CALCA and neoplasm: In the MOC2 model, Calca was expressed in about 70% of neurons from sham mice (23/36 male, 27/36 female) and 90% of neurons from MOC2-tumor bearing mice (32/36 male, 33/36 female, Figure 3D), and similar to the MOC1 model, the relative expression was significantly greater in tumor-bearing female mice compared to female PID14 sham (p = 0.048, Figure 3H).