CALCA and neoplasm: In the MOC1 model (Figure 3C), Calca was expressed in about 75% of neurons from sham PID40 mice (26/36 male, 28/36 female) and 85% of neurons from MOC1-tumor bearing mice (30/36 male, 31/36 female), however the relative expression was significantly greater in only tumor-bearing female mice compared to sham (p = 0.013, Figure 3E).