PTPRC and neoplasm: In the MOC2 model, there was no significant interaction between time, sex, and treatment for CD45+ cell infiltrate in the tongue tissue, but rather a significant effect of treatment [i.e., sham vs. MOC2 tumor; F(1,12) = 201.9, p < 0.0001] where there was significantly more CD45+ cell infiltrate in MOC2 tumor bearing mice compared to sham (Figures 5B,D).