ATF3 and cancer: Therefore, for this concise characterization, we chose to focus on cancer-induced changes in the pain-related genes Calca and Trpv1, as well as the injury marker, Atf3. Intact TG from MOC1- (PID40) and MOC2- (PID14) bearing mice were probed for the target genes using qPCR; relative fold change in expression was calculated to respective time and sex-matched sham mice for both groups.