While Atf3 was expressed in the majority of neurons from sham mice (34/36 male, 34/36 female) and MOC1-tumor bearing mice (35/36 male, 34/36 female, Figure 3C), the relative expression was significantly greater in neurons from male (p = 0.008) but not female (p = 0.467) tumor-bearing mice compared to neurons from sex-matched sham (Figure 3G). The gene discussed is ATF3; the disease is neoplasm.