When assessing the sexes individually, there was a significant increase in the percentage of DiI-positive CGRP-IR neurons and TRPV1-IR in TG sections from MOC1 tumor-bearing male (p = 0.009, p = 0.002 respectively) and female (p = 0.002, p = 0.001 respectively) mice and compared to sex-matched PID40 sham mice. Here, CALCA is linked to neoplasm.