Analysis according to A1c at study entry showed that poorly-controlled subjects had significantly longer duration of T2DM (9.0 ± 5.9 years vs 5.0 ± 4.5 years, p = 0.02), higher average A1c for the prior year (9.0 ± 1.9% vs 6.8 ± 1.0%, p < 0.001), lower 25-hydroxyvitamin D (23.8 ± 11.3 ng/mL vs 33.1 ± 14.7 ng/mL, p = 0.02), lower SHBG (22.0 ± 12.6 nmol/L vs 30.5 ± 11.3 nmol/L p = 0.02), and lower BMD at the total hip (1.062 ± 0.16 g/cm2 vs 1.159 ± 0.16 g/cm2, p = 0.05) (Supplementary Table 2). Here, SHBG is linked to type 2 diabetes mellitus.