Moreover, when the transcriptome analysis data of the PASMCs isolated from IPAH patients was analyzed, it was indicated that the target DEGs of HNRNPA2B1 were related to cAMP, p53, and Wnt signaling pathways, cell proliferation, and cell adhesion (Figures 8C,E). This evidence concerns the gene HNRNPA2B1 and idiopathic pulmonary arterial hypertension.