Moreover, when the transcriptome analysis data of the PASMCs isolated from IPAH patients was analyzed, it was indicated that the target DEGs of HNRNPA2B1 were related to cAMP, p53, and Wnt signaling pathways, cell proliferation, and cell adhesion (Figures 8C,E). Here, TP53 is linked to idiopathic pulmonary arterial hypertension.