Analysis of clinical survival data has indicated that the survival rate was higher in SKCM patients with a high expression of DYPD, DYPS, LYN, PRKCQ, and TLR1, while the survival rate was lower in patients with a high expression of GPI, MMP2, and PCSK9. In the detection of tumor tissue and normal tissue, it was shown that the expression of GPI, LYN, and TLR1 was enhanced, whereas the expression of MMP2 was reduced. Here, MMP2 is linked to neoplasm.