Besides, chemokine signal pathway (in UCS, THCA, PCPG, LAML, and KIRP), pathway in cancer (in THYM, PCPG, and OV) and drug metabolism (in SKCM, LGG, and ACC) were also potential signaling pathways modulated by CREB3L1 in pan-cancer (Supplementary Figure S5). Here, CREB3L1 is linked to cancer.