CREB3L1 and cancer: A remarkable correlation between CREB3L1 and TMB was identified in 18 cancers, a positive correlation was found in COAD, ESCA, LGG, PAAD, STAD, THCA, and THYM, while a negative correlation was suggested in ACC, BLCA, BRCA, CESC, HNSC, KIRC, KIRP, LIHC, LUAD, LUSC, and SKCM (Figure 9A).