CREB3L1 and cancer: A strongly positive correlation was found between CREB3L1 expression and T regulatory cells in ESCA, and macrophages, including M0 macrophages in DLBC and LGG, M1 macrophages in KIRP, and M2 macrophages in TGCT, while a negative relationship between CREB3L1 expression and B naïve cells was detected in PAAD and TGCT, indicating that group with high CREB3L1 expression had a higher infiltrating level of immune cells, which is in line with that high CREB3L1 expression levels being connected with higher immune scores in several cancer types.