In comparison, CREB3L1 expression levels were abnormally downregulated in tumor samples in 7 cancer types, including bladder urothelial carcinoma (BLCA), colon adenocarcinoma (COAD), kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), lung squamous cell carcinoma (LUSC), pheochromocytoma and paraganglioma (PCPG) and rectum adenocarcinoma (READ). This evidence concerns the gene CREB3L1 and pheochromocytoma-paraganglioma.