The finding of decreased FKBP5 DNA methylation associated with response to psychotherapy replicates the results of previous studies in individuals with PTSD who were treated with exposure therapy (Yehuda et al., 2013), children with anxiety disorders treated with cognitive behavioral therapy (Roberts et al., 2015) and individuals with Agoraphobia with or without panic disorder (Roberts et al., 2019). This evidence concerns the gene FKBP5 and panic disorder.