SPPL2C and neurodegenerative disease: Those traits and their associated genes include: neurodegenerative diseases (SPPL2C, NSF, MAPT, KANSL1, CRHR1), neuropsychiatric disorders (KANSL1, FOXO3, CRHR1), neuroticism (NSF, MAPT, KANSL1, FOXO3, CRHR1), intellectual performance (NSF, FOXO3), reaction time (NSF, MAPT, LRRC37A2, FOXO3, ARL17A), cognitive function (MAPT, LRRC37A2, KANSL1, FOXO3, CRHR1, ARL17A), educational attainment (MAPT, FOXO3, CRHR1) and mathematical ability (FOXO3, CRHR1).