PTPRC and neoplasm: scRNA-seq was performed on CD24–CD45– stromal cells and CD45+ immune cells from both Dptwt/wtTgfbr2fl/fl and Dptki/kiTgfbr2fl/fl tumours (Extended Data Fig. 1c).After quality control, dimensionality reduction and clustering, four main groups of cells were identified, each represented by cells from multiple animals (Extended Data Fig. 1d).