However, for patients with ARDS, average albumin had no obvious correlation with all-cause mortality on the 14th and 28th day after adjusting the covariates of heart rate, SBP, mean arterial pressure, diastolic pressure, respiratory rate, temperature, SPO2, platelet, potassium, sodium, creatinine, hemoglobin, WBC, AST, BNP, LVEF, diuretic, ACEI/ARB/ARNI and cardiac glycoside (HR 1.04 95% CI 0.80–1.35, P = 0.7858; HR 0.77 95% CI 0.55–1.08, P = 1344). The gene discussed is NPPB; the disease is acute respiratory distress syndrome.