Reactivity genes such as Tgm1, Cd22, Serpina3n, Spi1, and Timp1 showed highly correlated congruent elevated expression in both NPC and host astrocytes in SCI (Supplementary Fig. 14, Fig. 7l), consistent with findings that many astrocyte reactivity genes after SCI are not detectably expressed in either healthy astrocytes67 or NPC. The gene discussed is CD22; the disease is nasopharyngeal carcinoma.