All other medication classes investigated in OS reached only very low quality of evidence: ACE‐inhibitors, antibiotics, oral anticoagulants, antidepressants, antiparkinsonian drugs, benzodiazepines, beta‐blockers, calcium‐channel blockers, digoxin, diuretics, H1‐ and H2‐antihistamines, heparin, Insulin, NSAIDs, paracetamol, opioids, propofol and polypharmacy (as a delirium‐associated drug entity). Here, INS is linked to delirium.