Western blot analyses of 24 pairs of HCCs collected in our laboratory consistently demonstrated that MECOM and MIST1 expression were positively correlated (r = 0.5670; P = 0.0039); (Figure S9C), indicating the clinical relevancy of MECOM/MIST1 in HCC specimens. The gene discussed is BHLHA15; the disease is hepatocellular carcinoma.