CD274 and neoplasm: Noteworthy, the group treated with FerH nanocomplexes coupled with anti-PD-L1 under NIR irradiation significantly suppressed the tumor proliferation with an inhibition rate of 59.8% (Figure 5B), which indicated that FerH-mediated PTT combined with anti-PD-L1 could achieve a synergistic effect for the inhibition of distant tumors beyond laser irradiation.