In investigating the molecular mechanisms underlying the specific upregulation of WEE2-AS1 in GBM, we identified IGF2BP3, an m6A reader and a member of the IGF2BP family, which could promote the stability of target RNAs and thereby regulate their expression 40,41, playing a carcinogenic role in the malignant progression of GBM 22,42. The gene discussed is IGF2BP3; the disease is glioblastoma.