In addition, immunohistochemistry (IHC) analysis indicated that the expression of Ki67 (a proliferation marker) and N-cadherin (an invasiveness marker) in WEE2-AS1-knockdown tumor tissues was lower than that in the vector group, while WEE2-AS1 overexpression showed the opposite results (Figure S3C-D). The gene discussed is CDH2; the disease is neoplasm.