Interestingly, low ARHGAP24 was also associated with shorter OS in patients with other tumors, such as renal cell carcinoma (P < 0.001), lung cancer (P < 0.05) and pancreatic ductal adenocarcinoma (P = 0.045) (Figure S3A-E), suggesting its common inhibitory role in tumors. The gene discussed is ARHGAP24; the disease is hereditary clear cell renal cell carcinoma.