Prostate-specific membrane antigen (PSMA), also known as glutamate carboxypeptidase II, N-acetyl-L-aspartyl-L-glutamate peptidase I and folate hydrolase 1, is a transmembrane enzyme that is highly expressed on prostate cancer cells and in tumor-associated neovasculature of other cancers 1. This evidence concerns the gene FOLH1 and cancer.