Notably, 4-day FGFRi withdrawal led to more 18F-FDG accumulation in tumor (~2.3-fold increase in SUVmean on Day 10 compared with that on Day 6; p < 0.05), as well as the increased HK2 (Figure 5D) and Ki67 levels (Figure 5E). This evidence concerns the gene MKI67 and neoplasm.