In a previous study, we demonstrated that every 1-unit increase in CRP increased the risk of severe disease by 0.06%.17 We have previously reported that after controlling for other variables, every unit increase in CRP increased the risk of death by 0.4% among admitted black patients.18 A meta-analysis also revealed elevated CRP leading to poor outcomes in COVID-19 patients (OR, 11.97; 95% CI 4.97–28.8; P < .001). The gene discussed is CRP; the disease is COVID-19.