Because the levels of these cytokines were shown to be increased in the serum of patients developing acute and chronic GVHD and inhibition of CD132 could have a profound effect on GVHD [20], CD132 expression on the armored CAR-T cells was examined, and the expression level of CD132 was the lowest for CAR-T cells together with IL-15 and IL-15Ra compared with CD19-CAR-T and CD19-CAR-IL-15 T. This evidence concerns the gene IL15 and graft versus host disease.