NUBPL and otitis media: (Table 3, Fig. 1, Supplementary Fig. 2) Two variants in nucleotide binding protein like (NUBPL) gene, the G allele of rs113235453 (OR, 1.50; 95% CI [1.30–1.73]; p = 3.04 × 10–8) and the A allele of rs74633202 (OR, 1.50; 95% CI [1.30–1.73]; p = 3.05 × 10–8) were associated with increased risk of otitis media.