We replicated 3 associations with p <  = 0.05 and the same direction of effect as Tian’s report: herpes zoster with the A allele of rs7047299(IFNA21 gene, odds ratio [OR], 1.18; 95% confidence interval [CI], [1.06–1.32]; p = 0.0026) and the C allele of rs2808290 (close to MKX gene, OR, 1.09; 95% CI [1.02–1.16]; p = 0.0096); and otitis media with the C allele of rs114947103 (CDHR3 gene, OR, 1.09; 95% CI [1.00–1.18]; p = 0.0407) (Table 2). Here, IFNA21 is linked to otitis media.