PNPLA3 and liver disorder: The G/G‐genotype of PNPLA3 was associated with a higher rate of developing severe liver disease compared with the C/C genotype in both the crude analysis (HR 2.14, 95% CI = 1.17–3.91) and when adjusting for age, sex, T2D and BMI (aHR 2.27, 95% CI = 1.15–4.47) (Table 3).