CATSPER2 and deafness: The second most common cause was a multigene deletion that involved STRC and CATSPER2 (OMIM 607249); in males, this is associated with deafness-infertility syndrome.10 The next most common variants were in USH2A and STRC. More detailed categorization by diagnostic genes and variants of all 517 children can be found in eTable 2 in the Supplement.