SMC2 and cancer: It has been earlier reported that ARC, CAPE, Cuc-B, Wi-A and Wi-N cause growth arrest/apoptosis of cancer cells through multiple mechanisms of action (Bhargava et al., 2018; Garg et al., 2020; Malik et al., 2021; Narayanaswamy et al., 2014; Nigam et al., 2015; Radhakrishnan et al., 2021; Wadhwa et al., 2016) (Vaishnavi et al., 2012).