Among them, cell adhesion molecule 1 (CADM1) is an apoptosis-inducing tumor suppressor that is inactivated by methylation in a variety of tumor types, which may play a role in chemotherapy-induced cell death in AML (Fisser et al., 2015), but the other 5 genes’ role was rarely reported in AML. This evidence concerns the gene CADM1 and neoplasm.