It can be seen from the data in Figure 2 that lncRNA-PVT1 can affect the migration and invasion of rat LCC by regulating the expression of MMP9, regulating the expression of MMP9 by knocking down lncRNA-PVT1 can reduce the migration rate of LCC by 27.4%, and the invasion ability the level dropped by 21.6%. This evidence concerns the gene PVT1 and leukoencephalopathy with calcifications and cysts.