In this paper, QRT-PCR detection found that lncRNA-pvt1 is highly expressed in the study of the relationship between apoptosis of LCC huh7, hepg2, and mmpsmmc-7721, suggesting that lncRNA-pvt1 may be used as a proto-oncogene to control the normal occurrence and development of LCC. The gene discussed is PVT1; the disease is leukoencephalopathy with calcifications and cysts.