Based on the KEGG pathway enrichment analysis, 155 items were identified, including lipid and atherosclerosis, apoptosis, NOD-like receptor signaling pathway, PI3K-Akt signaling pathway, autophagy-animal, mitophagy-animal, mTOR signaling pathway, p53 signaling pathway, etc., (Figure 2A). The gene discussed is TP53; the disease is atherosclerosis.