The CXCL13 : CXCR5 axis might be involved in the promotion of lung cancer, and the B cell chemoattractant chemokine (CXCL13) is elevated in NSCLC patients, suggesting that it could be used as a predictor of the risk of early-stage lung adenocarcinoma [126]. This evidence concerns the gene CXCR5 and non-small cell lung carcinoma.