TP53 and cancer: The top 10 mutated cancer genes observed in the weighted China pan-cancer dataset were TP53 (51.4%), LRP1B (13.4%), PIK3CA (11.6%), KRAS (11.1%), EGFR (10.6%), APC (10.5%), KMT2D (9.7%), KMT2C (8.8%), ARID1A (8.4%), and FAT4 (7.7%).