In addition, our data indicated that among IL-19 receptor heterodimer, IL-20R2 was upregulated following infection of AECs with SARS-CoV-2 as well as in nasopharyngeal swabs of COVID-19 patients, suggesting that IL-20R2 could be the main receptor through which IL-19 signals during SARS-CoV-2 infection. The gene discussed is IL20RB; the disease is COVID-19.