For example, DMD is known to be a cancer gene50 in human myogenic tumors, such as gastrointestinal stromal tumors52, rhabdomyosarcoma53, and leiomyosarcoma54, and we find it is a putative driver gene in esophageal cancer where 54% of the cohort carries SVs in this region (Fig. 6a). The gene discussed is DMD; the disease is esophageal cancer.