SFXN2 and Miyoshi myopathy: To investigate the oncogenic role of SFXN2, we established two human MM cell lines ARP1 and H929, which stably overexpressed SFXN2 cDNA (SFXN2-OE) or inducibly knocked down SFXN2 (SFXN2-KD) based on the lentivirus system (Figs. 1e and S1).