KEGG pathway enrichment analysis indicated that 13 important signaling pathways were significantly enriched in the highly expressed ADRB2 phenotypes, including the JAK STAT signaling pathways, leukocyte trans-endothelial migration, chemokine signaling pathway, autoimmune, thyroid disease, Fc epsilon ri signaling pathway, intestinal immune network for iga production, cytokine receptor interaction, B cell receptor signaling pathway, NK cell-mediated cytotoxicity, allograft rejection, Mapk signaling pathway, T cell receptor signaling pathway, and NSCLC. The gene discussed is SOAT1; the disease is non-small cell lung carcinoma.