In addition, both univariate and multivariate Cox survival analyses suggested that HDAC7 was an independent prognostic factor for ESCC patients (HR = 2.200, 95% CI 1.471–3.290, P < 0.001; HR = 1.999, 95% CI 1.321–3.027, P = 0.001, Table 2). Here, HDAC7 is linked to esophageal squamous cell carcinoma.