MYC and esophageal squamous cell carcinoma: The expression of c-Myc was higher in the ESCC than their paired normal tissues (P < 0.001, Fig. 3b), and ESCC tissues from the high pTNM stage (III) had higher c-Myc expression than those with low pTNM stage (I & II) (P = 0.010, Fig. 3b).