We found that TMSB10 was positively correlated with the enrichment scores of typical cancer hallmarks, the inflammatory response and tumor malignancy markers (PCNA, a proliferation index, and VIM and CD44, markers of invasion) in a wide range of cancer types, especially in lower grade glioma (LGG), glioblastoma (GBM), bladder cancer (BLCA) and liver hepatocellular carcinoma (LIHC) (Fig. 2A). The gene discussed is PCNA; the disease is central nervous system cancer.