Previous research has demonstrated that AIM2 functions as a suppressor in multiple kinds of tumours, such as prostate cancer [36], colon cancer [37], melanoma [38], melanoma [39], and breast cancer but as a promoter in NSCLC (non-small cell lung cancer) [40], OSCC (oral squamous cell carcinoma) [41], and HPV (human papillomavirus)-associated cervical cancer [42]. Here, AIM2 is linked to melanoma.