Thirteen genes (NLRP2, TP63, CYCS, CASP9, IL1A, CHMP2B, CHMP4C, CHMP3, IL1B, CHMP7, TIRAP, CASP6, and GSDME) were downregulated and 31 other genes (CHMP2A, IRF2, CHMP6, TP53, GPX4, CASP3, PLCG1, NOD1, GSDMD, CASP8, CHMP4A, IL18, IL6, IRF1, NLRP1, CASP4, BAX, NLRP3, NLRP6, GSDMA, CASP1, GSDMB, NLRC4, PYCARD, NLRP7, GSDMC, NOD2, GZMB, CASP5, AIM2, GZMA) upregulated in tumour tissue samples. Here, CASP3 is linked to neoplasm.