Reports showed that miR-423-5p takes part in the regulation of the development of various tumors, such as aggravating the development of lung adenocarcinoma by targeting CADM1,32 targeting GRIM-19 to promote the progression of prostate cancer,33 and targeting STMN1 to inhibit the proliferation and invasion of osteosarcoma.34 Here, STMN1 is linked to lung adenocarcinoma.